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首页-小分子抑制剂&激动剂-Others-Other Targets-GSD-16-24
GSD-16-24

Chemical Structure : GSD-16-24

CAS No.:

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GSD-16-24

货号: PC-23153Not For Human Use, Lab Use Only.

GSD-16-24 is a small molecule inhibitor of amyloid fibrils of α-synuclein (α-syn), binds directly to the C-terminal IDR of α-syn monomer and fibril, preventing the fibril from binding to the receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GSD-16-24 is a small molecule inhibitor of amyloid fibrils of α-synuclein (α-syn), binds directly to the C-terminal IDR of α-syn monomer and fibril, preventing the fibril from binding to the receptors.

物理化学性质&存储条件

分子量 434.50
分子式 C24H26N4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(6-(4-methylpiperazin-1-yl)naphthalen-2-yl)methyl (3-(hydroxycarbamoyl)phenyl)carbamate

参考文献

1. Zhang S, et al. J Am Chem Soc. 2024 Sep 27. doi: 10.1021/jacs.4c08869.

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