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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-GS-9822
GS-9822

Chemical Structure : GS-9822

CAS No.: 2219362-41-9

GS-9822 (GS9822;GS 9822)

货号: PC-63539Not For Human Use, Lab Use Only.

GS-9822 (GS9822) is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 3 nM, potently inhibits the LEDGF/p75-integrase interaction with IC50 of 70 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GS-9822 (GS9822) is a potent, non-catalytic site HIV integrase inhibitor with wild type EC50 of 3 nM, potently inhibits the LEDGF/p75-integrase interaction with IC50 of 70 nM.

    物理化学性质&存储条件

    分子量 659.242
    分子式 C36H39ClN4O4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (S)-2-(tert-butoxy)-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-3-(1-(oxetan-3-yl)piperidin-4-yl)-1H-indazol-5-yl)benzo[d]thiazol-6-yl)acetic acid

    参考文献

    1. Bruggemans A, et al. Antimicrob Agents Chemother. 2023 May 1;65(5):e02328-20.

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