GS-5245 (Obeldesivir, ATV006) | Antiviral | Probechem Biochemicals

Chemical Structure : GS-5245

CAS No.: 2647441-36-7

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GS-5245 (Obeldesivir, GS 5245, ATV006)

货号: PC-21075Not For Human Use, Lab Use Only.

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥3980	In stock
50 mg	￥5880	In stock
100 mg		Get quote

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生物&药学活性

GS-5245 (Obeldesivir, ATV006) is an orall bioavailable, 5'-isobutyryl ester prodrug of GS-441524, exhibits strong SARS-CoV-2 antiviral efficacy both in vitro and in vivo.

物理化学性质&存储条件

分子量	361.36
分子式	C16H19N5O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl isobutyrate

参考文献

1. Richard L. Mackman, et al. J. Med. Chem. 2023.
2. Cao L, et, al. Sci Transl Med. 2022 May 17:eabm7621.

GS-5245 (Obeldesivir, GS 5245, ATV006)

生物&药学活性

物理化学性质&存储条件

参考文献

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GS-5245 (Obeldesivir, GS 5245, ATV006)

生物&药学活性

物理化学性质&存储条件

参考文献

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