GRA Ex-25

Chemical Structure : GRA Ex-25

CAS No.: 307983-31-9

加入收藏

货号: PC-45839Not For Human Use, Lab Use Only.

GRA Ex-25 is a potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors.

规格	价格	库存
2 mg	￥780	In stock
5 mg	￥1280	In stock
10 mg	￥1980	In stock
25 mg	￥2980	In stock
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GRA Ex-25 is a potent glucagon receptor inhibitor with IC50 of 56 and 55 nM for rat and human glucagon receptors.
GRA Ex-25 binds to human glucagon receptor with Ki of 63 nM, moderately inhibits glucagon induced adenylate cyclase (Ki=254 nM).
GRA Ex-25 significantly reduces blood glucose caused by exogenous administration of glucagon in rat model (3 mg/kg, i.v.).

物理化学性质&存储条件

分子量	563.6085
分子式	C29H36F3N3O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 32 mg/mL
Chemical Name/SMILES	β-Alanine, N-[4-[[[trans-4-(1,1-dimethylethyl)cyclohexyl][[[4-(trifluoromethoxy)phenyl]amino]carbonyl]amino]methyl]benzoyl]-

参考文献

1. Kurukulasuriya R, et al. Bioorg Med Chem Lett. 2004 May 3;14(9):2047-50.

2. Lau J, et al. J Med Chem. 2007 Jan 11;50(1):113-28.

GRA Ex-25

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GRA Ex-25

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.