GPRP acetate | Fibrin inhibitor | Probechem Biochemicals

Chemical Structure : GPRP acetate

CAS No.: 157009-81-9

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GPRP acetate (Gly-Pro-Arg-Pro acetate, Pefabloc FG)

货号: PC-47483Not For Human Use, Lab Use Only.

GPRP acetate (Pefabloc FG) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin, inhibits the spontaneous polymerization of fibrin monomers.

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10 mg	￥1280	In stock
25 mg	￥2280	In stock
50 mg	￥3880	In stock
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生物&药学活性

GPRP acetate (Pefabloc FG) is a peptide corresponding partly to the amino terminus of the Aα chain and Bβ chain of fibrin, inhibits the spontaneous polymerization of fibrin monomers.
GPRP acetate also inhibits ADP-induced platelet aggregation with IC50 of 3 mM.
GPRP acetate binds to the fibrinogen D domain, and inhibits the ability of fibrinogen to bind to the platelet membrane glycoprotein GPIIb/IIIa.

物理化学性质&存储条件

分子量	485.5346
分子式	C20H35N7O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	100 mM in H2O
Chemical Name/SMILES	L-Proline, glycyl-L-prolyl-L-arginyl-, acetate (1:1)

参考文献

1. Laudano AP, et al. Proc Natl Acad Sci U S A. 1978 Jul;75(7):3085-9.

2. Plow EF, et al. Proc Natl Acad Sci U S A. 1982 Jun;79(12):3711-5.

3. Adelman B, et al. Circ Res. 1990 Oct;67(4):941-7.

GPRP acetate (Gly-Pro-Arg-Pro acetate, Pefabloc FG)

生物&药学活性

物理化学性质&存储条件

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GPRP acetate (Gly-Pro-Arg-Pro acetate, Pefabloc FG)

生物&药学活性

物理化学性质&存储条件

参考文献

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