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GPR52 agonist 1

Chemical Structure : GPR52 agonist 1

CAS No.: 1207965-40-9

GPR52 agonist 1 (GPR52 agonist-1)

货号: PC-26921Not For Human Use, Lab Use Only.

GPR52 agonist 1 is a potent, BBB- penetrant and orally available agonist of orphan G-protein-coupled receptor 52 (GPR52) with pEC50 of 7.53, suppresses methamphetamine-induced hyperactivity in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GPR52 agonist 1 is a potent, BBB- penetrant and orally available agonist of orphan G-protein-coupled receptor 52 (GPR52) with pEC50 of 7.53, suppresses methamphetamine-induced hyperactivity in vivo.

物理化学性质&存储条件

分子量 453.96
分子式 C25H21ClFNO2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-[2-(3-Chloro-5-fluorobenzyl)-1-benzothiophen-7-yl]-N-(2-methoxyethyl)benzamide

参考文献

1. Setoh M, et al. J Med Chem. 2014 Jun 26;57(12):5226-37.

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