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首页-小分子抑制剂&激动剂-GPCR-Proton-sensing GPCRs-GPR4 antagonist 39c
GPR4 antagonist 39c

Chemical Structure : GPR4 antagonist 39c

CAS No.: 1197879-16-5

GPR4 antagonist 39c

货号: PC-20836Not For Human Use, Lab Use Only.

GPR4 antagonist 39c is a potent and orally active GPR4 antagonist with IC50 of 110 nM.

规格 价格 库存 数量
25 mg Get quote
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1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GPR4 antagonist 39c is a potent and orally active GPR4 antagonist with IC50 of 110 nM.
GPR4 antagonist 39c shows potent cellular activity and is efficacious in animal models of angiogenesis, inflammation and pain.

物理化学性质&存储条件

分子量 431.63
分子式 C27H37N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

CC1=C2C(N(CC3=CC=C(/C=C/CN4CCN(C(C)C)CC4)C=C3)C(CC)=N2)=NC(C)=C1

参考文献

1. Wolfgang Miltz, et al. Bioorg Med Chem. 2017 Aug 15;25(16):4512-4525.

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