GPR43 agonist compound 187

Chemical Structure : GPR43 agonist compound 187

加入收藏

货号: PC-24795Not For Human Use, Lab Use Only.

GPR43 agonist compound 187 is a potent, selective GPR43 (FFAR2 or FFA2) agonist, induces Rho GTPase signaling to activate YAP/TAZ, causes YAP/TAZ accumulated in the nucleus in GPR43-expressing HEK293 cells in a manner dependent on Gα12/13 and Gαq/11.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

物理化学性质&存储条件

分子量	419.48
分子式	C19H22FN5O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-[(2R,6S)-2, 6-dimethylmorpholin-4-yl]-7-(2-fluorobenzenesulfonyl)-2- methyl-5H-pyrrolo[3,2-d]pyrimidin-6-amine

参考文献

1. Bi-Oh Park, et al. Mol Cells. 2021 Jul 31;44(7):458-467.

2. Patent WO2015198045.

3. Xuan Zhang, et al. Nature. 2025 Jun 18. doi: 10.1038/s41586-025-09186-6.