GPR40 agonist AP4

Chemical Structure : GPR40 agonist AP4

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货号: PC-20869Not For Human Use, Lab Use Only.

GPR40 agonist AP4 is a potent, selective, full allosteric agonist (AgoPAM) of GPR40 with EC50 of 0.08 nM, Emax=283%.

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GPR40 agonist AP4 is a potent, selective, full allosteric agonist (AgoPAM) of GPR40 with EC50 of 0.08 nM, Emax=283%.

分子量	574.74
分子式	C35H43FN2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	O=C(O)[C@@H](C)[C@@H](C1CC1)C2=CC3=C(C=C2)CC[C@H](C4=CC=C(C5=CC(OC)=NC=C5F)C(CN(C(C)C)C(C)C)=C4)O3

1. Jun Lu, et al. GPR40 agonist AP8, Nat Struct Mol Biol . 2017 Jul;24(7):570-577.

2. Patent WO2016022742 A1.