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首页-小分子抑制剂&激动剂-Wnt/Notch/Hedgehog-Porcupine-GNF-1331
GNF-1331

Chemical Structure : GNF-1331

CAS No.: 603101-22-0

GNF-1331 (GNF1331)

货号: PC-49488Not For Human Use, Lab Use Only.

GNF-1331 is a potent, selective inhibitor of Porcupine, binds to PORCN in a radioligand binding assay with IC50 of 8 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GNF-1331 is a potent, selective inhibitor of Porcupine, binds to PORCN in a radioligand binding assay with IC50 of 8 nM.

    物理化学性质&存储条件

    分子量 440.54
    分子式 C20H20N6O2S2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(6-methoxybenzo[d]thiazol-2-yl)-2-((4-propyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide

    参考文献

    1. Cheng D, et al. ACS Med Chem Lett. 2016 May 10;7(7):676-80.

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