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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-GNE-8324
GNE-8324

Chemical Structure : GNE-8324

CAS No.: 1698901-76-6

GNE-8324 (GNE8324)

货号: PC-22453Not For Human Use, Lab Use Only.

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GNE-8324 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM), binds to the GluN1/GluN2A LBD dimer interface.

物理化学性质&存储条件

分子量 343.42
分子式 C18H18FN3OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-[[Ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-4H,6H-cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one

参考文献

1. David H Hackos, et al. Neuropharmacology. 2017 Jan;112(Pt A):34-45.

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