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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-GNE-6901
GNE-6901

Chemical Structure : GNE-6901

CAS No.: 1698900-69-4

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GNE-6901 (GNE6901)

货号: PC-22454Not For Human Use, Lab Use Only.

GNE-6901 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM) wIth EC50 of 382 nM, binds to the GluN1/GluN2A LBD dimer interface.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GNE-6901 is a selective GluN2A containing NMDAR positive allosteric modulator (PAM) wIth EC50 of 382 nM, binds to the GluN1/GluN2A LBD dimer interface.

物理化学性质&存储条件

分子量 360.40
分子式 C18H17FN2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5H-Thiazolo[3,2-a]pyrimidin-5-one, 7-[(4-fluorophenoxy)methyl]-3-[(1R,2R)-2-(hydroxymethyl)cyclopropyl]-2-methyl-

参考文献

1. David H Hackos, et al. Neuropharmacology. 2017 Jan;112(Pt A):34-45.

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