GNE-207 |Cas:2158266-58-9 Buy GNE-207 from ProbeChem, Global Biochemicals Supplier

Chemical Structure : GNE-207

加入收藏

GNE-207 (GNE207;GNE 207)

货号: PC-60307Not For Human Use, Lab Use Only.

GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.

规格	价格	库存	数量
25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
1 g		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GNE-207 (GNE207) is a novel potent, selective, orally active CBP/p300 bromodomain with IC50 of 1.0 nM.
GNE-207 displays >2,500-fold selectivity over BRD4.
GNE-207 suppresses Myc transcript levels in MV-4-11 cellular assays with EC50 of 18 nM.
GNE-207 exhibits a good pharmacokinetic profile.

物理化学性质&存储条件

分子量	510.598
分子式	C29H30N6O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(8-(5-acetyl-1-(tetrahydro-2H-pyran-4-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)isoquinolin-3-yl)-N-methylpicolinamide

参考文献

1. Lai KW, et al. Bioorg Med Chem Lett. 2018 Jan 1;28(1):15-23.

GNE-207 (GNE207;GNE 207)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GNE-207 (GNE207;GNE 207)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.