GM6001 | MMP inhibitor | Probechem Biochemicals

Chemical Structure : GM6001

CAS No.: 142880-36-2

加入收藏

GM6001 (Ilomastat, GM 6001, Galardin)

货号: PC-21093Not For Human Use, Lab Use Only.

GM6001 (Ilomastat) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 of 1.5/1.1/1.9/0.5 nM for MMP-1/2/3/9, respectively.

规格	价格	库存
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GM6001 (Ilomastat) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor with IC50 of 1.5/1.1/1.9/0.5 nM for MMP-1/2/3/9, respectively.
GM6001 inhibits human skin fibroblast collagenase, thermolysin and elastase with Ki values of 0.4 nM, 20 nM, 20 nM, resepctively.
GM6001 (0.1-10 nM) inhibits gelatinase A and gelatinase B produced by T-cells, inhibits T-cell homing.
GM6001 significantly suppresses intimal hyperplasia and intimalcollagen content in vivo.

物理化学性质&存储条件

分子量	388.47
分子式	C20H28N4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N4-Hydroxy-N1-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide

参考文献

1. Grobelny D, et al. Biochemistry. 1992 Aug 11;31(31):7152-4.

2. Leppert D, et al. 1995 May 1;154(9):4379-89.

GM6001 (Ilomastat, GM 6001, Galardin)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GM6001 (Ilomastat, GM 6001, Galardin)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.