GLUT4-IN-17 |CAS:1061081-61-5 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glucose Transporter (GLUT)-GLUT4-IN-17

Chemical Structure : GLUT4-IN-17

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GLUT4-IN-17

货号: PC-60884Not For Human Use, Lab Use Only.

A potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

GLUT4-IN-17 is a potent, selective glucose transporter 4 (GLUT4) inhibitor with IC450 of 10.8 uM, inhibits MM cell proliferation.
GLUT4-IN-17 reduces ATB-BMPA binding to GLUT4 to a much greater extent than to GLUT1, inhibits 2-DOG uptake in GLUT4-expressing cells.

物理化学性质&存储条件

分子量	509.654
分子式	C31H35N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3-((3-((methyl(quinolin-6-ylmethyl)amino)methyl)phenoxy)methyl)piperidin-1-yl)(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)methanone

参考文献

1. Mishra RK, et al. J Biol Chem. 2015 Jun 5;290(23):14441-53.

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GLUT4-IN-17

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生物&药学活性

物理化学性质&存储条件

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