GLPG-0492 R enantiomer |CAS:1215085-93-0 Probechem Biochemicals

首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Androgen Receptor (AR)-GLPG-0492 R enantiomer

Chemical Structure : GLPG-0492 R enantiomer

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GLPG-0492 R enantiomer (GLPG0492 R enantiomer)

货号: PC-45422Not For Human Use, Lab Use Only.

The R enantiomer of GLPG-0492, a non-steroidal selective androgen receptor modulator (SARM) for treatment for Duchenne muscular dystrophy (DMD).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

The R enantiomer of GLPG-0492, a non-steroidal selective androgen receptor modulator (SARM) for treatment for Duchenne muscular dystrophy (DMD); shows weak potency (1.25 uM) compared with GLPG-0492.

物理化学性质&存储条件

分子量	389.328
分子式	C19H14F3N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzonitrile, 4-[(4R)-4-(hydroxymethyl)-3-methyl-2,5-dioxo-4-phenyl-1-imidazolidinyl]-2-(trifluoromethyl)-

参考文献

1. Nique F, et al. J Med Chem. 2012 Oct 11;55(19):8236-47.

2. Cozzoli A, et al. Pharmacol Res. 2013 Jun;72:9-24.

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GLPG-0492 R enantiomer (GLPG0492 R enantiomer)

生物&药学活性

物理化学性质&存储条件

参考文献

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GLPG-0492 R enantiomer (GLPG0492 R enantiomer)

生物&药学活性

物理化学性质&存储条件

参考文献

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