GK563 |CAS:1983928-04-6 Probechem Biochemicals

Chemical Structure : GK563

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GK563 (GK-563;GK 563)

货号: PC-36137Not For Human Use, Lab Use Only.

GK563 (GK-563) is a potent, selective inhibitor of Ca2+-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM, >20,000-fold selectivity over GIVA cPLA2.

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生物&药学活性

GK563 (GK-563) is a potent, selective inhibitor of Ca2+-independent phospholipase A2 (GVIA iPLA2) with IC50 of 1 nM, >20,000-fold selectivity over GIVA cPLA2.
GK563 reduce β-cell apoptosis induced by proinflammatory cytokines.

物理化学性质&存储条件

分子量	246.35
分子式	C16H22O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	trans-3-(4-Phenylbutyl)-4-propyloxetan-2-one

参考文献

1. Dedaki C, et al. J Med Chem. 2019 Mar 12. doi: 10.1021/acs.jmedchem.8b01216.

GK563 (GK-563;GK 563)

生物&药学活性

物理化学性质&存储条件

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GK563 (GK-563;GK 563)

生物&药学活性

物理化学性质&存储条件

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