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GH8HA01

Chemical Structure : GH8HA01

CAS No.:

GH8HA01

货号: PC-49539Not For Human Use, Lab Use Only.

GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GH8HA01 is a highly potent, selective HDAC8 inhibitor with Ki of 0.67 nM, highly selective against HDAC8 compared to other HDACs.

    物理化学性质&存储条件

    分子量 1091.189
    分子式 C55H66N10O14
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (3S,6S,9S,12S,15S,18S,21S)-9-((1H-indol-3-yl)methyl)-21-amino-12,15-dibenzyl-3-carbamoyl-6-(2-carboxyethyl)-18-(6-(hydroxyamino)-6-oxohexyl)-22-(4-hydroxyphenyl)-5,8,11,14,17,20-hexaoxo-4,7,10,13,16,19-hexaazadocosanoic acid

    参考文献

    1. Jared S Morse, et al. Protein Sci. 2022 Nov 16;e4512.

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