GFRα2/GFRα23 inhibitor 16

Chemical Structure : GFRα2/GFRα23 inhibitor 16

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货号: PC-22671Not For Human Use, Lab Use Only.

GFRα2/GFRα23 inhibitor 16 is a selective small moelcule inhibitor of glycosylphosphatidylinositol-anchored co-receptor GFRa2/GFRa3 with IC50 of 0.1/0.2 uM respectively, selective over RET.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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GFRα2/GFRα23 inhibitor 16 is a selective small moelcule inhibitor of glycosylphosphatidylinositol-anchored co-receptor GFRa2/GFRa3 with IC50 of 0.1/0.2 uM respectively, selective over RET.

物理化学性质&存储条件

分子量	589.74
分子式	C36H39N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-2-cyclohexyl-N-methyl-2-(2-(3-(((R)-5-(2-(phenylamino)pyrimidin-5-yl)-2,3-dihydro-1H-inden-2-yl)oxy)phenyl)acetamido)acetamide

参考文献

1. Shea L Johnson, et al. Bioorg Med Chem Lett. 2024 Jul 12:129889.