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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Estrogen Receptor/ERR-GDC-0927 R-form
GDC-0927 R-form

Chemical Structure : GDC-0927 R-form

CAS No.: 1642297-53-7

GDC-0927 R-form (GDC0927 R-form)

货号: PC-63334Not For Human Use, Lab Use Only.

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer..

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

GDC-0927 (SRN-927, RG-6047) is a potent, orally bioavailable, selective estrogen receptor degrader (SERD) for treatment of metastatic hormone receptor-positive/HER2-negative breast cancer.

物理化学性质&存储条件

分子量 461.533
分子式 C28H28FNO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)phenyl)-3-(3-hydroxyphenyl)-4-methyl-2H-chromen-6-ol

参考文献

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