GDC-0425 |CAS:1200129-48-1 Probechem Biochemicals

Chemical Structure : GDC-0425

CAS No.: 1200129-48-1

加入收藏

GDC-0425 (RG-7602;RG7602;GDC0425)

货号: PC-60278Not For Human Use, Lab Use Only.

GDC-0425 (RG7602) is a potent, selective and orally active Chk1 inhibitor.

规格	价格	库存
10 mg	￥980	In stock
25 mg	￥1480	In stock
50 mg	￥2480	In stock
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

GDC-0425 (RG7602) is a potent, selective and orally active Chk1 inhibitor.
GDC-0425 (RG7602) enhances gemcitabine efficacy in tumor xenograft models.
GDC-0425 (RG7602) shows greater chemopotentiation in cancer cell lines lacking p53 activity.

物理化学性质&存储条件

分子量	321.384
分子式	C18H19N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-((1-ethylpiperidin-4-yl)oxy)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile

参考文献

1. Takahashi RH, et al. Drug Metab Dispos. 2017 May;45(5):430-440.

2. Infante JR, et al. Clin Cancer Res. 2017 May 15;23(10):2423-2432.

3. Lee HJ, et al. Mol Cancer Ther. 2017 Apr;16(4):694-704.

GDC-0425 (RG-7602;RG7602;GDC0425)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

GDC-0425 (RG-7602;RG7602;GDC0425)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.