Chemical Structure : GB1874
CAS No.: 1011440-46-2
货号: PC-73231Not For Human Use, Lab Use Only.
GB1874 is an inhibitor of the Wnt pathway that targets the β-catenin-TCF4 interaction.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥2580 | In stock | |
10 mg | ¥3980 | In stock | |
25 mg | ¥5880 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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GB1874 is an inhibitor of the Wnt pathway that targets the β-catenin-TCF4 interaction.
GB1874 affected the proliferation and stemness of Wnt-addicted colorectal cancer (CRC) cells in vitro.
GB1874 inhibited the growth of CRC tumor xenografts in vivo.
分子量 | 421.559 | |
分子式 | C24H27N3O2S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2-((5-((4-ethylphenoxy)methyl)-4-(1-phenylethyl)-4H-1,2,4-triazol-3-yl)thio)cyclopentan-1-one |
1. Yannick D Benoit, et al. Cell Chem Biol. 2021 Oct 21;28(10):1394-1406.e10.
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