Chemical Structure : GB111-NH2
CAS No.: 956479-18-8
货号: PC-61355Not For Human Use, Lab Use Only.
GB111-NH2 (Z-Phe-Lys-AOMK) is a novel cysteine cathepsin inhibitor that blocks the activity of cathepsins B, L and S.
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GB111-NH2 (Z-Phe-Lys-AOMK) is a novel cysteine cathepsin inhibitor that blocks the activity of cathepsins B, L and S.
GB111-NH2 (Z-Phe-Lys-AOMK) inhibits autophagy and increases oxidative stress, specifically trigger macrophage cell death.
分子量 | 573.68 | |
分子式 | C33H39N3O6 | |
外观性状 | Solid | |
储存条件 |
|
|
Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
(S)-7-amino-3-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)-2-oxoheptyl 2,6-dimethylbenzoate |
1. Salpeter SJ, et al. Oncogene. 2015 Dec 10;34(50):6066-78.
2. Blum G, et al. Nat Chem Biol. 2005 Sep;1(4):203-9.
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