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GAPDS

Chemical Structure : GAPDS

CAS No.: 917773-99-0

GAPDS (GAPDH inhibitor GAPDS)

货号: PC-62489Not For Human Use, Lab Use Only.

GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    GAPDS is a small molecule that targets the glycolytic enzyme glyceraldehyde 3-phosphate dehydrogenase (GAPDH).
    GAPDS significantly reduces cellular ATP, shows greater toxicity against cancer cells compared to 6-OHDA, also selectively inhibits cell migration and invasion.
    GAPDS reduces GAPDH levels in the cytoplasm, and has potent anticancer activity in vivo.

    物理化学性质&存储条件

    分子量 573.654
    分子式 C30H35N7O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(2-(2-(2-((4-((3,4-dihydroxyphenethyl)amino)-6-(phenylamino)-1,3,5-triazin-2-yl)amino)ethoxy)ethoxy)ethyl)benzamide

    参考文献

    1. Jung DW, et al. Chem Biol. 2014 Nov 20;21(11):1533-45.

    2. Min J, et al. Nat Chem Biol. 2007 Jan;3(1):55-9.

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