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Furmonertinib mesylate

Chemical Structure : Furmonertinib mesylate

CAS No.: 2130958-55-1

Furmonertinib mesylate (AST2818, AST-2818, Alflutinib mesylate)

货号: PC-35641Not For Human Use, Lab Use Only.

Furmonertinib mesylate (AST-2818, Alflutinib mesylate) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Furmonertinib mesylate (AST-2818, Alflutinib mesylate) is a third generation EGFR mutation selective tyrosine kinase inhibitor, inhibits EGFR active mutations as well as T790M acquired resistant mutation.

物理化学性质&存储条件

分子量 664.705
分子式 C29H35F3N8O5S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)-6-(2,2,2-trifluoroethoxy)pyridin-3-yl)acrylamide methanesulfonate

参考文献

1. PCT Int. Appl. (2017), WO 2017152707 A1 20170914.

2. PCT Int. Appl. (2017), WO 2017152706 A1 20170914.

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