Furin inhibitor 9

Chemical Structure : Furin inhibitor 9

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货号: PC-26216Not For Human Use, Lab Use Only.

Furin inhibitor 9 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 12.4 nM, weakly inhibits the structurally related PC7 with Ki of 278 nM, shows antiviral potency against the furin-dependent H7N7 influenza A strain SC35M.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

物理化学性质&存储条件

分子量	913.70
分子式	C32H44Cl2N4O.3C2HF3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Acetamide, N-[[1-[[5-([4,4′-bipiperidin]-1-ylmethyl)-3′,5′-dichloro[1,1′-biphenyl]-3-yl]methyl]-4-piperidinyl]methyl]-, 2,2,2-trifluoroacetate (1:3)

参考文献

1. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.