Furin inhibitor 27

Chemical Structure : Furin inhibitor 27

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货号: PC-26215Not For Human Use, Lab Use Only.

Furin inhibitor 27 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 1.67 nM, also inhibits the structurally related PC7 with Ki of 7.27 nM.

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250 mg		Get quote

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生物&药学活性

Furin inhibitor 27 is a highly potent, small molecule inhibitor of proprotein convertase (PC) furin with Ki of 1.67 nM, also inhibits the structurally related PC7 with Ki of 7.27 nM.

物理化学性质&存储条件

分子量	566.57
分子式	C31H37Cl2N5O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1-((3',5'-Dichloro-5-((4-(pyridin-4-yl)-piperazin-1-yl)-methyl)-[1,1'-biphenyl]-3-yl)-methyl)-piperidin-4-yl)-methyl)-acetamide

参考文献

1. Lange RW, et al. J Med Chem. 2025 Nov 30. doi: 10.1021/acs.jmedchem.5c02157.