Fumarate hydratase-IN-1 | Fumarase inhibitor | Probechem Biochemicals

Chemical Structure : Fumarate hydratase-IN-1

CAS No.: 1644060-37-6

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Fumarate hydratase-IN-1 (Fumarase inhibitor 1)

货号: PC-42018Not For Human Use, Lab Use Only.

Fumarate hydratase-IN-1 is a cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle).

规格	价格	库存
5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4580	In stock
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Fumarate hydratase-IN-1 is a cell-permeable small molecule inhibitor of Fumarase (fumarate hydratase), an enzyme of the tricarboxylic acid cycle (TCA cycle).
Fumarate hydratase-IN-1 elicits a nutrient-dependent cytotoxicity in a number of cancer cell lines, and displays increased growth-inhibitory activity toward SW620 cell line grown in the absence of glucose.

物理化学性质&存储条件

分子量	446.5381
分子式	C27H30N2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3aH-Indole-3a-carboxylic acid, 1-([1,1'-biphenyl]-4-ylmethyl)-1,2,3,4,5,6-hexahydro-3-[2-(methylamino)-2-oxoethyl]-2-oxo-, ethyl ester, (3R,3aS)-rel-

参考文献

1. Takeuchi T, et al. J Am Chem Soc. 2015 Jan 21;137(2):564-7.

Fumarate hydratase-IN-1 (Fumarase inhibitor 1)

生物&药学活性

物理化学性质&存储条件

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Fumarate hydratase-IN-1 (Fumarase inhibitor 1)

生物&药学活性

物理化学性质&存储条件

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