Fumagillin | MetAP2 inhibitor | Probechem Biochemicals

Chemical Structure : Fumagillin

CAS No.: 23110-15-8

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Fumagillin (Amebacilin, NSC9168)

货号: PC-22787Not For Human Use, Lab Use Only.

Fumagillin (NSC9168) is an antimicrobial compound that covalently binds and inhibits the methionine aminopeptidase MetAP-2, inhibits angiogenesis and cancer cell proliferation.

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5 mg	￥1780	In stock
10 mg	￥2980	In stock
25 mg	￥4980	In stock
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生物&药学活性

Fumagillin (NSC9168) is an antimicrobial compound that covalently binds and inhibits the methionine aminopeptidase MetAP-2, inhibits angiogenesis and cancer cell proliferation.
Fumagillin can inhibits HIV‐1 infection through the inhibition of HIV-1 viral protein R (Vpr) activity.

物理化学性质&存储条件

分子量	458.55
分子式	C26H34O7
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2E,4E,6E,8E)-10-(((3R,4S,5S,6R)-5-methoxy-4-((2R,3R)-2-methyl-3-(3-methylbut-2-en-1-yl)oxiran-2-yl)-1-oxaspiro[2.5]octan-6-yl)oxy)-10-oxodeca-2,4,6,8-tetraenoic acid

参考文献

1. Sin N, et al. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6099-103.

2. Griffith EC, et al. Chem Biol. 1997 Jun;4(6):461-71.

3. Griffith EC, et al. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15183-8.

Fumagillin (Amebacilin, NSC9168)

生物&药学活性

物理化学性质&存储条件

参考文献

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Fumagillin (Amebacilin, NSC9168)

生物&药学活性

物理化学性质&存储条件

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