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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-Fulzerasib
Fulzerasib

Chemical Structure : Fulzerasib

CAS No.: 2641747-54-6

Fulzerasib (IBI351, IBI-351, GFH925)

货号: PC-20037Not For Human Use, Lab Use Only.

Fulzerasib (IBI351, IBI-351) is a potent covalent and irreversible inhibitor of KRAS G12C.

规格 价格 库存 数量
25 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Fulzerasib (IBI351, IBI-351, GFH925) is a potent covalent and irreversible inhibitor of KRAS G12C.

    物理化学性质&存储条件

    分子量 617.08
    分子式 C32H30ClFN6O4
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4aR)-3-acryloyl-11-chloro-10-(2-fluoro-6-hydroxyphenyl)-8-(2-isopropyl-4-methylpyridin-3-yl)-6-methyl-2,3,4,4a,6,8-hexahydro-1H-pyrazino[1',2':4,5]pyrazino[2,3-c][1,8]naphthyridine-5,7-dione

    参考文献

    1. Patent WO2021083167 A1

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