Foxy-5 | Wnt5A agonist | Probechem Biochemicals

Chemical Structure : Foxy-5

CAS No.: 881188-51-8

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Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu, Foxy5)

货号: PC-61759Not For Human Use, Lab Use Only.

Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility.

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5 mg	￥2480	In stock
10 mg	￥3980	In stock
25 mg	￥5980	In stock
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100 mg		Get quote

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生物&药学活性

Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu) is a Wnt5A mimicking hexapeptide that inhibits breast cancer metastasis in vivo by targeting cell motility.
Foxy-5 also significantly inhibits the initial metastatic dissemination of prostate cancer cells to regional and distal lymph nodes.
Foxy-5 specifically targets invasion without affecting apoptosis or viability of WNT5A-low prostate cancer cells.

物理化学性质&存储条件

分子量	694.77
分子式	C26H42N6O12S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S,5S,8R,14S)-5-(2-carboxyethyl)-14-((S)-2-formamido-4-(methylthio)butanamido)-2-isobutyl-8-(mercaptomethyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazahexadecanedioic acid

参考文献

1. Säfholm A, et al. Clin Cancer Res. 2008 Oct 15;14(20):6556-63.

2. Ford CE, et al. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3919-24.

3. Canesin G, et al. PLoS One. 2017 Sep 8;12(9):e0184418.

Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu, Foxy5)

生物&药学活性

物理化学性质&存储条件

参考文献

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Foxy-5 (formyl-Met-Asp-Gly-Cys-Glu-Leu, Foxy5)

生物&药学活性

物理化学性质&存储条件

参考文献

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