Foslinanib (TRX-818, CVM-1118) sodium | TRAP1 inhibitor

Chemical Structure : Foslinanib sodium

CAS No.: 1256037-62-3

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Foslinanib sodium (TRX-818 sodium, CVM-1118 sodium)

货号: PC-35451Not For Human Use, Lab Use Only.

Foslinanib (TRX-818, CVM-1118) sodium is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities, promotes apoptosis and inhibits vasculogenic mimicry via targeting TRAP1.

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10 mg	￥5280	In stock
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生物&药学活性

Foslinanib (TRX-818, CVM-1118) induces cancer cell apoptosis and inhibits cancer cell proliferation,.

Foslinanib (TRX-818, CVM-1118) also prevents tumor cell VM by blocking the formation of vasculogenic-like tubular structures through an as of yet undetermined mechanism of action.

物理化学性质&存储条件

分子量	393.218
分子式	C16H11FNNa2O5P
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium (2-(3-fluorophenyl)-6-methoxy-4-oxo-1,4-dihydroquinolin-5-yl)phosphonate

参考文献

1. Lifen Shen, et al. Pathol Oncol Res. 2023 Jun 7:29:1611038.

Foslinanib sodium (TRX-818 sodium, CVM-1118 sodium)

生物&药学活性

物理化学性质&存储条件

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Foslinanib sodium (TRX-818 sodium, CVM-1118 sodium)

生物&药学活性

物理化学性质&存储条件

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