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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Angiotensin-converting Enzyme (ACE)-Fosfenopril
Fosfenopril

Chemical Structure : Fosfenopril

CAS No.: 95399-71-6

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Fosfenopril (Fosinoprilat, Fosinoprilic acid, SQ 27519)

货号: PC-27009Not For Human Use, Lab Use Only.

Fosfenopril (Fosinoprilat, SQ 27519) is the active moiety of the prodrug fosinopril and potent angiotensin I converting enzyme (ACE) inhibitor with IC50 of 11 nM for purified rabbit lung ACE.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Fosfenopril (Fosinoprilat, SQ 27519) is the active moiety of the prodrug fosinopril and potent angiotensin I converting enzyme (ACE) inhibitor with IC50 of 11 nM for purified rabbit lung ACE.

物理化学性质&存储条件

分子量 435.50
分子式 C23H34NO5P
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,4S)-4-Cyclohexyl-1-(2-(hydroxy(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylic acid

参考文献

1. DeForrest JM, et al. J Cardiovasc Pharmacol. 1989 Nov;14(5):730-6.

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