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Fmoc-Val-Cit-PAB-PNP

Chemical Structure : Fmoc-Val-Cit-PAB-PNP

CAS No.: 863971-53-3

Fmoc-Val-Cit-PAB-PNP

货号: PC-45818Not For Human Use, Lab Use Only.

A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).

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500 mg ¥6500 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A cathepsin B-cleavable dipeptide linker for antibody-drug-conjugation (ADC).

物理化学性质&存储条件

分子量 766.7957
分子式 C40H42N6O10
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 40 mg/mL

Chemical Name/SMILES

L-Ornithinamide, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]methyl]phenyl]-

参考文献

1. Dubowchik GM, et al. Bioconjug Chem. 2002 Jul-Aug;13(4):855-69.

2. Doronina SO, et al. Bioconjug Chem. 2008 Oct;19(10):1960-3.

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