Fluorothiazinone

Chemical Structure : Fluorothiazinone

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货号: PC-26780Not For Human Use, Lab Use Only.

Fluorothiazinone is a small molecule antivirulent compound that suppresses the formation of biofilms, inhibits the type III secretion system (T3SS) in Gram-negative bacteria.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

Fluorothiazinone is a small molecule antivirulent compound that suppresses the formation of biofilms, inhibits the type III secretion system (T3SS) in Gram-negative bacteria.
Fluorothiazinone inhibits motility of P. aeruginosa, P. mirabilis, and E. coli in a dose-dependent manner.
Fluorothiazinone selectively inhibits flagellum-based motility in Gram-negative bacteria.
Fluorothiazinone interferes with flagellum biosynthesis rather than disruption of rotation.

物理化学性质&存储条件

分子量	421.42
分子式	C19H17F2N3O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2,4-difluorophenyl)-4-(3-ethoxy-4-hydroxybenzyl)-5-oxo-5,6-dihydro-4H-1,3,4-thiadiazine-2-carboxamide

参考文献

1. Tsarenko SV, et al. J Antibiot (Tokyo). 2023 Jul;76(7):397-405.

2. Zigangirova NA, et al. Antibiotics (Basel). 2024 May 22;13(6):476.

3. Slonov A, et al. Antibiotics (Basel). 2025 Aug 11;14(8):820.