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首页-小分子抑制剂&激动剂-Autophagy-Autophagy-related Protein (Atg)-Flubendazole
Flubendazole

Chemical Structure : Flubendazole

CAS No.: 31430-15-6

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Flubendazole

货号: PC-26069Not For Human Use, Lab Use Only.

Flubendazole is an anthelmintic drug and inhibitor of tubulin polymerization and disruption of microtubule function, also activates ATG4B, induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy.

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500 mg ￥980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Flubendazole is an anthelmintic drug and inhibitor of tubulin polymerization and disruption of microtubule function, also activates ATG4B, induces apoptosis in human colorectal cancer (CRC) by blocking the STAT3 signaling axis and activation of autophagy.

物理化学性质&存储条件

分子量 313.29
分子式 C16H12FN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Methyl (5-(4-fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamate

参考文献

1. Shichong Lin, et al. J Exp Clin Cancer Res. 2019 Jul 8;38(1):293.

2. Zhou X, et al. Cell Death Discov. 2018 Feb 14;4:18.

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