Firategrast (SB683699) | α4β1/α4β7 integrin antagonist

Chemical Structure : Firategrast

CAS No.: 402567-16-2

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Firategrast (SB683699, SB 683699, SB-683699)

货号: PC-28555Not For Human Use, Lab Use Only.

Firategrast (SB683699) is a potent, specific and orally active α4β1/α4β7 integrin antagonist, reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity.

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10 mg	￥1180	In stock
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生物&药学活性

Firategrast (SB683699) is a potent, specific and orally active α4β1/α4β7 integrin antagonist, reduces trafficking of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity.

物理化学性质&存储条件

分子量	499.51
分子式	C27H27F2NO6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(2,6-difluorobenzamido)-3-(4'-(ethoxymethyl)-2',6'-dimethoxy-[1,1'-biphenyl]-4-yl)propanoic acid

参考文献

1. Moses O. Evbuomwan, et al. Blood (2017) 130 (Supplement 1): 3197.

2. Miller DH, et al. Lancet Neurol. 2012 Feb;11(2):131-9.

Firategrast (SB683699, SB 683699, SB-683699)

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Firategrast (SB683699, SB 683699, SB-683699)

生物&药学活性

物理化学性质&存储条件

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