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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-5alpha Reductase-Finasteride
Finasteride

Chemical Structure : Finasteride

CAS No.: 98319-26-7

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Finasteride (MK-906, MK906)

货号: PC-24014Not For Human Use, Lab Use Only.

Finasteride (MK-906) is a potent, selective, orally active and competitive 5 alpha-reductase (5α-reductase) inhibitor with IC50 of 4.2 nM (type II 5α-reductase), >100-fold selective over type I 5α-reductase.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Finasteride (MK-906) is a potent, selective, orally active and competitive 5 alpha-reductase (5α-reductase) inhibitor with IC50 of 4.2 nM (type II 5α-reductase), >100-fold selective over type I 5α-reductase.

物理化学性质&存储条件

分子量 372.55
分子式 C23H36N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

参考文献

1. Flores E, et, al. Mini Rev Med Chem. 2003 May;3(3):225-37.

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