Fidaxomicin (OPT-80, PAR-101) |CAS 873857-62-6 Probechem Biochemicals

Chemical Structure : Fidaxomicin

CAS No.: 873857-62-6

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Fidaxomicin (OPT-80, PAR-101)

货号: PC-45367Not For Human Use, Lab Use Only.

Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL.

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50 mg	￥580	In stock
100 mg	￥880	In stock
250 mg	￥1480	In stock
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生物&药学活性

Fidaxomicin (OPT-80, PAR-101) is a new class of narrow spectrum macrocyclic antibiotic drug and RNA polymerase inhibitor, shows potent anti-Clostridium difficile activity with MIC90 of 0.12 ug/mL.
Fidaxomicin treatmen induced selective eradication of pathogenic Clostridium difficile with minimal disruption to the multiple species of bacteria.

物理化学性质&存储条件

分子量	1058.039
分子式	C52H74Cl2O18
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 33 mg/mL
Chemical Name/SMILES	Oxacyclooctadeca-3,5,9,13,15-pentaen-2-one, 3-[[[6-deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1

参考文献

1. Poxton IR, et al. Future Microbiol. 2010 Apr;5(4):539-48.
2. Ackermann G, et al. Antimicrob Agents Chemother. 2004 Jun;48(6):2280-2.

Fidaxomicin (OPT-80, PAR-101)

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Fidaxomicin (OPT-80, PAR-101)

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