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Fexlamose

Chemical Structure : Fexlamose

CAS No.: 1285607-08-0

Fexlamose (AER-01, AER 01, MUC-031, MUC031)

货号: PC-26907Not For Human Use, Lab Use Only.

Fexlamose (AER-01, MUC-031) is a potent and fast-acting mucolytic compound, cleaves disulfides to cause mucolysis, shows potential for muco-obstructive lung diseases like COPD (Chronic Obstructive Pulmonary Disease) and asthma.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Fexlamose (AER-01, MUC-031) is a potent and fast-acting mucolytic compound, cleaves disulfides to cause mucolysis, shows potential for muco-obstructive lung diseases like COPD (Chronic Obstructive Pulmonary Disease) and asthma.
Fexlamose (AER-01, MUC-031) is a thiol-modified carbohydrate designed to break down mucus plugs in the airways.
Fexlamose (AER-01, MUC-031) decreases airway mucus plugging, lessens airway inflammation and improves survival in βENaC-Tg mice.
MUC-031 is a more potent and faster acting mucolytic than N-acetylcysteine (NAC) and recombinant human deoxyribonuclease I (rhDNase).

物理化学性质&存储条件

分子量 374.42
分子式 C12H22O9S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2S,3S,4S,5R,6R)-2-(sulfanylmethyl)-6-[(2R,3R,4S,5S,6S)-3,4,5-trihydroxy-6-(sulfanylmethyl)oxan-2-yl]oxyoxane-3,4,5-triol

参考文献

1. Annalisa Addante, et al. Eur Respir J. 2023 May 25;61(5):2202022.

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