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Ferrostatin-1

Chemical Structure : Ferrostatin-1

CAS No.: 347174-05-4

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Ferrostatin-1 (Ferrostatin 1, Fer-1)

货号: PC-35744Not For Human Use, Lab Use Only.

Ferrostatin-1 is a potent ferroptosis inhibitor with IC50 of 33 nM, inhibits erastin-induced ferroptosis in HT-1080 cells with EC50 of 60 nM.

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10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2180 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Ferrostatin-1 (Fer 1) is a potent ferroptosis inhibitor with IC50 of 33 nM, inhibits erastin-induced ferroptosis in HT-1080 cells with EC50 of 60 nM.
Ferrostatin-1 (Fer 1) prevents erastin-induced accumulation of cytosolic and lipid ROS.
Ferrostatin-1 (Fer 1) does not inhibit ERK phosphorylation or arrest the proliferation of HT-1080 cells.

物理化学性质&存储条件

分子量 262.353
分子式 C15H22N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

ethyl 3-amino-4-(cyclohexylamino)benzoate

参考文献

1. Devisscher L, et al. J Med Chem. 2018 Oct 25. doi: 10.1021/acs.jmedchem.8b01299.

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