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首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis-FerroLOXIN-2
FerroLOXIN-2

Chemical Structure : FerroLOXIN-2

CAS No.: 2773428-34-3

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FerroLOXIN-2

货号: PC-20924Not For Human Use, Lab Use Only.

FerroLOXIN-2 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

FerroLOXIN-2 is a specific, small-molecule inhibitor of ferroptosis, inhibits 15LOX/PEBP1 catalytic complex rather than 15LOX alone, effectively suppresses ferroptosis in vitro and in vivo.

物理化学性质&存储条件

分子量 490.30
分子式 C23H16BrF4N3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

FC1=CC(N2C=C(C3=CC=CC=C3)N=C2NCC4=CC=C(C(F)(F)F)C(Br)=C4)=CC=C1

参考文献

1. Haider H Dar, et al. Proc Natl Acad Sci U S A. 2023 Jun 20;120(25):e2218896120.

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