欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Apoptosis-Ferroptosis-Ferfluor-1
Ferfluor-1

Chemical Structure : Ferfluor-1

CAS No.: 3030473-59-4

加入收藏

Ferfluor-1 (Ferfluor 1, Ferfluor1)

货号: PC-24078Not For Human Use, Lab Use Only.

Ferfluor-1 is a potent, selective ferroptosis inhibitor, rescues ferroptotic cell death on HT1080 cells with EC50 of 57 nM, also is a specific ferroptosis photoluminescence imaging probe.

规格 价格 库存 数量
25 mg Get quote
50 mg Get quote
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Ferfluor-1 is a potent, selective ferroptosis inhibitor, rescues ferroptotic cell death on HT1080 cells with EC50 of 57 nM, also is a specific ferroptosis photoluminescence imaging probe.
    Ferfluor-1 exhibits improved in vitro/in vivo absorption, distribution, metabolism, and elimination (ADME) characteristics and optimal BBB permeability comnpare with Fer-1.
    Ferfluor-1 shows potent anti-ferroptosis with EC50 values of 57, 75, 2.3 nM in HT1080, OS-RC-2 and SH-SY5Y cells, respectively.
    Ferfluor-1 exhibits authentic behavior like Fer-1 as being a specific ferroptosis inhibitor.
    Ferfluor-1 exhibits a maximum absorption peak at 350 nm and a fluorescent (FL) emission peak at 525 nm with a large Stokes shift of 175 nm in phosphate-buffered saline (PBS) (with 0.5% DMSO, 37 ℃, pH =7.4).
    Ferfluor-1 is a specific ferroptosis probe has been explored in both living cells and in vivo zebrafish.
    Ferfluor-1 is a potential tool for ferroptosis-related diagnostic and therapeutic applications in the central nervous system.

    物理化学性质&存储条件

    分子量 288.41
    分子式 C15H20N4S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N1-cyclohexyl-4-(5-methyl-1,3,4-thiadiazol-2-yl)benzene-1,2-diamine

    参考文献

    1. Yan J, et al. Angew Chem Int Ed Engl. 2025 Feb 21:e202502195.

    备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

    联系我们 sales@probechem.com

    Bulk Inquiry

    * Indicates a Required FieldYour information is safe with us.

    • *Product name:
    • *Applicant name:
    • *Email address:
    • *Organization name:
    • *Requested quantity:
    • *Country:
    • *Additional Information:

    询单

    • *产品名称:
    • *姓名:
    • *邮箱:
    • *公司名称:
    • *询单数量:
    • *国籍:
    • 询单信息: