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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-Fenofibric acid
Fenofibric acid

Chemical Structure : Fenofibric acid

CAS No.: 42017-89-0

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Fenofibric acid (FNF acid)

货号: PC-23809Not For Human Use, Lab Use Only.

Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Fenofibric acid, an active metabolite of fenofibrate and anti-inflammatory agent, is a PPAR activitor with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively, also inhibits COX-2 with IC50 of 48 nM.

物理化学性质&存储条件

分子量 318.75
分子式 C17H15ClO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid

参考文献

1. Dietz M, et al. ChemMedChem. 2012 Jun;7(6):1101-11.

2. Prasad GS, et al. Inflammopharmacology. 2017 Dec 13.

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