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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HIV-Fangchinoline
Fangchinoline

Chemical Structure : Fangchinoline

CAS No.: 436-77-1

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Fangchinoline

货号: PC-27150Not For Human Use, Lab Use Only.

Fangchinoline is a natural bisbenzylisoquinoline alkaloid isolated from Stephania tetrandra whtinin extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis, inhibits HIV-1 replication by impairing gp160 proteolytic processing, suppresses FAK-mediated signaling pathway in cancer cells which highly expressed FAK, enhances antigen cross-presentation in a DNGR-1 (CLEC9A)-dependent manner.

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25 mg ￥580 In stock
50 mg ￥880 In stock
100 mg ￥1280 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Fangchinoline is a natural bisbenzylisoquinoline alkaloid isolated from Stephania tetrandra whtinin extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis, inhibits HIV-1 replication by impairing gp160 proteolytic processing, suppresses FAK-mediated signaling pathway in cancer cells which highly expressed FAK, enhances antigen cross-presentation in a DNGR-1 (CLEC9A)-dependent manner.

物理化学性质&存储条件

分子量 608.74
分子式 C37H40N2O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(11S,31S)-16,36,54-Trimethoxy-12,32-dimethyl-11,12,13,14,31,32,33,34-octahydro-2,6-dioxa-1(7,1),3(8,1)-diisoquinolina-5(1,3),7(1,4)-dibenzenacyclooctaphan-37-ol

参考文献

1. Liao Y, et al. Adv Sci (Weinh). 2026 Jun 11:e76043.

2. Wan Z, et al. PLoS One. 2012;7(6):e39225.

3. Guo B, et al. J Drug Target. 2015 Apr;23(3):266-74.

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