Chemical Structure : Fadrozole hydrochloride
CAS No.: 102676-31-3
货号: PC-60699Not For Human Use, Lab Use Only.
Fadrozole (FAD286) hydrochloride is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.
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---|---|---|---|
10 mg | ¥780 | In stock | |
25 mg | ¥1280 | In stock | |
50 mg | ¥2180 | In stock | |
100 mg | ¥3580 | In stock | |
250 mg | Get quote |
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Fadrozole (FAD286) hydrochloride is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.
Fadrozole (FAD286) lowers ovarian estrogen synthesis by gonadotropin-primed, androstenedione treated mice, suppresses hormone-dependent and -independent tumors in vivo.
分子量 | 259.737 | |
分子式 | C14H14ClN3 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile hydrochloride |
1. Steele RE, et al. Steroids. 1987 Jul-Sep;50(1-3):147-61.
2. Schieweck K, et al. Cancer Res. 1988 Feb 15;48(4):834-8.
3. Juniewicz PE, et al. J Urol. 1988 Apr;139(4):827-31.
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