Fadrozole (CGS 16949A, FAD286) | Aromatase inhibitor | Probechem Biochemicals

Chemical Structure : Fadrozole

CAS No.: 102676-47-1

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Fadrozole (CGS 16949A, FAD286, FAD 286)

货号: PC-60698Not For Human Use, Lab Use Only.

Fadrozole (CGS 16949A, FAD286) is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.

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25 mg	￥1380	In stock
50 mg	￥2180	In stock
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生物&药学活性

Fadrozole (CGS 16949A, FAD286) is a potent and selective, orally bioavailable aromatase inhibitor with IC50 of 1.7 nM, 180 times more potent than aminoglutethimide.
Fadrozole lowers ovarian estrogen synthesis by gonadotropin-primed, androstenedione treated mice, suppresses hormone-dependent and -independent tumors in vivo.

物理化学性质&存储条件

分子量	223.279
分子式	C14H13N3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)benzonitrile

参考文献

1. Steele RE, et al. Steroids. 1987 Jul-Sep;50(1-3):147-61.

2. Schieweck K, et al. Cancer Res. 1988 Feb 15;48(4):834-8.

3. Juniewicz PE, et al. J Urol. 1988 Apr;139(4):827-31.

Fadrozole (CGS 16949A, FAD286, FAD 286)

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Fadrozole (CGS 16949A, FAD286, FAD 286)

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