FTO inhibitor FB23

Chemical Structure : FTO inhibitor FB23

CAS No.: 2243736-35-6

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货号: PC-22847Not For Human Use, Lab Use Only.

FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

规格	价格	库存
5 mg	￥1280	In stock
10 mg	￥1880	In stock
25 mg	￥2980	In stock

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生物&药学活性

FTO inhibitor FB23 is a potent and selective FTO demethylase inhibitor with IC50 of 60 nM, directly binds to FTO and selectively inhibits FTO's mRNA N6-methyladenosine (m6A) demethylase activity.

物理化学性质&存储条件

分子量	377.22
分子式	C18H14Cl2N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((2,6-Dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid

参考文献

1. Yue Huang, et al. Cancer Cell. 2019 Apr 15;35(4):677-691.e10.