FT895 (FT-895) | HDAC11 inhibitor | Probechem Biochemicals

Chemical Structure : FT895

CAS No.: 2225728-57-2

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FT895 (FT 895, FT-895)

货号: PC-35170Not For Human Use, Lab Use Only.

FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).

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5 mg	￥1880	In stock
10 mg	￥2980	In stock
25 mg	￥4880	In stock
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生物&药学活性

FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).
FT895 displays promising cellular activity (IC50<20 nM) and pharmacokinetic properties.
FT895 is a useful tool to study the biology of HDAC11 and shows potential use as a therapeutic target for oncology and inflammation indications.

物理化学性质&存储条件

分子量	352.317
分子式	C16H15F3N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-hydroxy-1,1-dimethyl-2-(5-(trifluoromethyl)pyrazin-2-yl)isoindoline-4-carboxamide

参考文献

1. Martin MW, et al. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.

FT895 (FT 895, FT-895)

生物&药学活性

物理化学性质&存储条件

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FT895 (FT 895, FT-895)

生物&药学活性

物理化学性质&存储条件

参考文献

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