Chemical Structure : FT895
CAS No.: 2225728-57-2
货号: PC-35170Not For Human Use, Lab Use Only.
FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1980 | In stock | |
10 mg | ¥2980 | In stock | |
25 mg | ¥4880 | In stock | |
50 mg | Get quote | ||
100 mg | Get quote |
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FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).
FT895 displays promising cellular activity (IC50<20 nM) and pharmacokinetic properties.
FT895 is a useful tool to study the biology of HDAC11 and shows potential use as a therapeutic target for oncology and inflammation indications.
分子量 | 352.317 | |
分子式 | C16H15F3N4O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
N-hydroxy-1,1-dimethyl-2-(5-(trifluoromethyl)pyrazin-2-yl)isoindoline-4-carboxamide |
1. Martin MW, et al. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.
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