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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-FT895
FT895

Chemical Structure : FT895

CAS No.: 2225728-57-2

FT895 (FT 895;FT-895)

货号: PC-35170Not For Human Use, Lab Use Only.

FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).

规格 价格 库存 数量
5 mg ¥1980 In stock
10 mg ¥2980 In stock
25 mg ¥4880 In stock
50 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

FT895 (FT-895) is a potent and selective inhibitor of HDAC11 with IC50 of 3 nM, displays no significant activity against HDAC1-10 (IC50>5 uM).
FT895 displays promising cellular activity (IC50<20 nM) and pharmacokinetic properties.
FT895 is a useful tool to study the biology of HDAC11 and shows potential use as a therapeutic target for oncology and inflammation indications.

物理化学性质&存储条件

分子量 352.317
分子式 C16H15F3N4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-hydroxy-1,1-dimethyl-2-(5-(trifluoromethyl)pyrazin-2-yl)isoindoline-4-carboxamide

参考文献

1. Martin MW, et al. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147.

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