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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-FT108
FT108

Chemical Structure : FT108

CAS No.: 2379645-28-8

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FT108 (FT-108)

货号: PC-72096Not For Human Use, Lab Use Only.

FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    FT108 (FT-108) is a potent, selective HDAC6 inhibitor (IC50=26 nM) relative to other HDAC family members (HDAC3 IC50=6.68 uM and HDAC8 IC50=4.07 uM).

    物理化学性质&存储条件

    分子量 320.345
    分子式 C16H20N2O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-hydroxy-4-(tetrahydro-2H-pyran-4-carbonyl)-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepine-8-carboxamide

    参考文献

    1. Lanzhu Yue, et al. Blood. 2020 Jan 16;135(3):191-207.

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